(Relatively uncontentious assertions appear as normal text.  Potentially contentious assertions appear like this.)
 

2010	Automatic translators allow monolingual humans to converse with any speaker of any major human language.
2015	Bandwidth has increased enormously due to fiber optics and spread-spectrum radio.
2020	Almost all overt tyranny has been eliminated. Physicists have confirmed that the fate of the universe is asymptotic expansion. Most text, images, audio, and video is produced and consumed digitally. Unauthorized reproduction and distribution of such media is routine. 1st Martian sample return has revealed no conclusive fossil evidence of life.
2030	20% of former fideists have become mystics. Radio astronomers have discovered signals from extraterrestrial intelligence. Computer display technology plateaus with cheap flat panels and retinal projectors.
2040	Physicists have completed a quantum unification theory. Personal bodily flight has become commercialized. Transonic flight still serves just a few intercontinental routes.
2050	Molecular biologists have detailed description of how life on Earth began. Computing is limited not by processing, storage, or bandwidth but by heat, latency, and batteries. Fresh water availability is now limited only by energy costs of transportation and desalinization. Automated vehicle/traffic control gives rail-like traffic flow to roads. Privacy is curtailed by commercial availability of mobile remote-controlled microsensors.
2075	Physicists have reached limits of knowing why fundamental physical laws are as they are. Hydrogen fuel cells are replacing internal combustion of fossil fuels. VTOL aircraft are as widely owned as RVs in 2000.
2100	Expected and maximum human longevity have increased by 30 years. Humans are able to record and archive all they ever see, hear, and say. Most of humanity is using a common currency descended from the American dollar. Unmanned radio observatory has been established on far side of moon.
2150	Remaining fideisms have diluted into agnostic mysticism; true fideists dwindle. Fusion provides major parts of humanity's power. Most psychotropic drugs are legal; addiction is prevented neurochemically.
2200	Permanent manned space stations in Earth orbit have been established. 1st artifactual life and artificial intelligence systems have been created and enfranchised. Obesity and other nutritional diseases are curable.
2300	1st Von Neumann probes have been dispatched from Earth. Most genetic, infectious, immunological, and cancerous disease is preventable or curable. Most of humanity enjoys Western standards of living and productivity.  Earth's population has stabilized at around 20 billion. The workweek has stabilized at around 20 hours.
2400	Extropian positivism has displaced most other belief systems.
2500	Heat pollution has become the last significant environmental problem. A truly global federal government exists.
2880	Asteroid 1950DA (1km wide) has a 1/300 chance of hitting Earth March 16.
3000	Humans have created on the moon their 1st self-sustaining extraplanetary colony. Earth has received 1st telemetry from unmanned probes to nearby stars.  Neurotechnologists have started to modify and augment natural human intelligence. Genetic engineers have designed first artificially-created species. English is the native language of 90% of humans. Floating communities and estates have become increasingly popular.
4000	1st embarkation of mobile space habitat toward nearby star. Humans culture animal tissue in bulk rather than raise animals en masse. As the next ice age begins, Earth is about 0.5C cooler (relative to 2000CE) than it otherwise would have been.
5000	Humans mass-produce intravenous liquid food.
10K	1st terraforming (of Mars or a Jovian moon) has started to show progress. Another 90Kyr-long ice age has begun, and Earth is about 3C cooler (relative to 2000CE) than it otherwise would have been.
16K	The precession of Earth's axis has made Vega the northern pole star.
23K	The 1679-bit 1974 Arecibo interstellar message finally covers the 21Kly distance to its target, the globular cluster M13 (300K stars).
100K	A majority of persons descended from H. sapiens lives beyond Earth.
250K	An object more than a kilometer wide will probably have struck Earth.  Earth's magnetic will by now probably have reversed, as it does every few hundred thousand years and as it last did 780Kya.
1M	A majority of persons descended from H. sapiens lives beyond the Solar system. The red dwarf Gliese 710, currently 63ly away, will pass within 0.5 ly of Sol and appear at 0.6 magnitude.
2M	Pioneer 10 (launched in 1972, 68 ly away) passes near Aldebaran at 44 Mm/h.
50M	Africa has collided with Europe (closing the Mediterranean), Australia has merged with SE Asia, and California has slid up the coast to Alaska
100M	Earth has information from probes to the Andromeda galaxy.
226M	Sol has completed one more orbit around the Milky Way's center.
250M	The Americas merge with Afro-Eurasia, reducing the (formerly growing) Atlantic to an inland sea.
1B	Earth has information from probes to every star system in the Milky Way.
2B	Increased Solar output has extincted any remaining Earth life due to runaway greenhouse effect.
6B	Sun ends its main-sequence life as a red giant large enough to engulf and possibly swallow Earth, and then cools into a white dwarf.  Milky Way and Andromeda galaxies collide.
10B	Milky Way galaxy's intelligent population stabilizes at its maximum.
100B	Living systems are huddled around red dwarfs for light and warmth.  The charred and frozen Earth-Moon system (if not already swallowed by Sol's red giant phase) has stabilized to a 47-day rotation/revolution at a distance of 560,000 km.
150B	Due to the universe's accelerating expansion, the view of everything outside the gravitationally-bound Local Group of galaxies stops changing and fades away.
1014	Almost all stars stopped shining, having become brown or white dwarfs. Little or no life remains.
1015	Planets have been dislodged from their solar systems by stellar close encounters.
1020	The remaining stars (brown or white dwarfs) have all either been dislodged from their galaxies, or collapsed into central galactic black holes. Dwarf collisions cease, and the last few stars formed thereby stop shining.
1040	Proton decay has left the universe with only black holes and subatomic particles.
10100	The last black hole evaporates, emitting the cold dark universe's final flash of visible light.